HCE (RNGTT) (NM_003800) Human Recombinant Protein
Product Specifications
Background
Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human RNA guanylyltransferase and 5'-phosphatase (RNGTT)
Synonyms
CAP1A; hCAP; HCE; HCE1
Gene ID
8732
UniProt
O60942, Q7Z3R6
Accession Number mRNA
NM_003800
Chromosomal Location
6q15
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
68.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RNGTT
Species
Human
Protein ID
NP_003791
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8732
Uniprot URL
https://www.uniprot.org/uniprot/O60942
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003800
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003791
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400994-100 1x 100 µL
TNF alpha (J2D10), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400178-500 1x 500 µL
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740460-500 1x 500 µL
CD44 Standard (156-3C11), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680012-100 1x 100 µL
Tyrosinase (T311), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682462-100 1x 100 µL
Ki-67 (Proliferating Cell Marker) (MKI67/2462), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881852-100 1x 100 µL
BCL10 (MALT-Lymphoma Marker) (151), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details