MYCBP (NM_012333) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]
Synonyms
AMY-1
Gene ID
26292
UniProt
Q99417
Accession Number mRNA
NM_012333
Chromosomal Location
1p34.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
ES Cell Differentiation/IPS, Transcription Factors
Molecular Weight
11.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MYCBP
Species
Human
Protein ID
NP_036465
Overview
Recombinant protein of human c-myc binding protein (MYCBP)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/26292
Uniprot URL
https://www.uniprot.org/uniprot/Q99417
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012333
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036465
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