MYD88 (NM_002468) Human Recombinant Protein
Product Specifications
Background
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Synonyms
IMD68; MYD88D
Gene ID
4615
UniProt
Q99836, A0A0A0MS70
Accession Number mRNA
NM_002468
Chromosomal Location
3p22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Apoptosis, Toll-like receptor signaling pathway
Field of Research
Apoptosis, Toll-like receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
33.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MYD88
Species
Human
Protein ID
NP_002459
Overview
Recombinant protein of human myeloid differentiation primary response gene (88) (MYD88)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4615
Uniprot URL
https://www.uniprot.org/uniprot/Q99836
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002468
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002459
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1189113-01 0.02 mg (E-Coli)
Recombinant Treponema pallidum subsp. pallidum UPF0102 protein TPASS_0913 (TPASS_0913)
Ask
View Details MBS1189113-02 0.1 mg (E-Coli)
Recombinant Treponema pallidum subsp. pallidum UPF0102 protein TPASS_0913 (TPASS_0913)
Ask
View Details 
MBS1189113-03 0.02 mg (Yeast)
Recombinant Treponema pallidum subsp. pallidum UPF0102 protein TPASS_0913 (TPASS_0913)
Ask
View Details MBS1189113-04 0.1 mg (Yeast)
Recombinant Treponema pallidum subsp. pallidum UPF0102 protein TPASS_0913 (TPASS_0913)
Ask
View Details