GTF3C2 (NM_001521) Human Recombinant Protein
Product Specifications
Background
Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.[UniProtKB/Swiss-Prot Function]
Synonyms
TFIIIC-BETA; TFIIIC110
Gene ID
2976
UniProt
Q8WUA4
Accession Number mRNA
NM_001521
Chromosomal Location
2p23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
100.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GTF3C2
Species
Human
Protein ID
NP_001512
Overview
Recombinant protein of human general transcription factor IIIC, polypeptide 2, beta 110kDa (GTF3C2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2976
Uniprot URL
https://www.uniprot.org/uniprot/Q8WUA4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001521
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001512
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