Profilin 1 (PFN1) (NM_005022) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]
Synonyms
ALS18
Gene ID
5216
UniProt
P07737
Accession Number mRNA
NM_005022
Chromosomal Location
17p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Regulation of actin cytoskeleton
Field of Research
Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
27991922
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency
Molecular Weight
14.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PFN1
Species
Human
Protein ID
NP_005013
Overview
Recombinant protein of human profilin 1 (PFN1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5216
Uniprot URL
https://www.uniprot.org/uniprot/P07737
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005022
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005013
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6130091-01 0.1 mL
ASB8 (Ankyrin Repeat and SOCS Box Protein 8, ASB-8, PP14212, FLJ21255, MGC5540) (AP)
Ask
View Details MBS6130091-02 5x 0.1 mL
ASB8 (Ankyrin Repeat and SOCS Box Protein 8, ASB-8, PP14212, FLJ21255, MGC5540) (AP)
Ask
View Details 
