Profilin 1 (PFN1) (NM_005022) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]

Overview

Recombinant protein of human profilin 1 (PFN1)

Synonyms

ALS18

Gene ID

5216

UniProt

P07737

Accession Number mRNA

NM_005022

Chromosomal Location

17p13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Regulation of actin cytoskeleton

Field of Research

Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

27991922

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Stem cell - Pluripotency

Molecular Weight

14.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.