Cytochrome b5 (CYB5A) (NM_148923) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Synonyms
CYB5; MCB5; METAG
Gene ID
1528
UniProt
P00167, A0A384ME44
Accession Number mRNA
NM_148923
Chromosomal Location
18q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
15.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CYB5A
Species
Human
Protein ID
NP_683725
Overview
Recombinant protein of human cytochrome b5 type A (microsomal) (CYB5A), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1528
Uniprot URL
https://www.uniprot.org/uniprot/P00167
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_148923
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_683725
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