SSH3 (NM_017857) Human Recombinant Protein

Product Specifications

Background

The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]

Overview

Recombinant protein of human slingshot homolog 3 (Drosophila) (SSH3)

Synonyms

SSH3L

Gene ID

54961

UniProt

Q8TE77, A0A024R5J4

Accession Number mRNA

NM_017857

Chromosomal Location

11q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Regulation of actin cytoskeleton

Field of Research

Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Phosphatase

Molecular Weight

72.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.