SSH3 (NM_017857) Human Recombinant Protein
Product Specifications
Background
The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]
Synonyms
SSH3L
Gene ID
54961
UniProt
Q8TE77, A0A024R5J4
Accession Number mRNA
NM_017857
Chromosomal Location
11q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Regulation of actin cytoskeleton
Field of Research
Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
72.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SSH3
Species
Human
Protein ID
NP_060327
Overview
Recombinant protein of human slingshot homolog 3 (Drosophila) (SSH3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54961
Uniprot URL
https://www.uniprot.org/uniprot/Q8TE77
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017857
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060327
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