Ketohexokinase (KHK) (NM_000221) Human Recombinant Protein

Product Specifications

Background

This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human ketohexokinase (fructokinase) (KHK), transcript variant a

Synonyms

Ketohexokinase; ketohexokinase (fructokinase)

Gene ID

3795

UniProt

P50053, A0A140VJM6

Accession Number mRNA

NM_000221

Chromosomal Location

2p23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Fructose and mannose metabolism, Metabolic pathways

Field of Research

Fructose and mannose metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

32.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.