Ketohexokinase (KHK) (NM_000221) Human Recombinant Protein
Product Specifications
Background
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
Ketohexokinase; ketohexokinase (fructokinase)
Gene ID
3795
UniProt
P50053, A0A140VJM6
Accession Number mRNA
NM_000221
Chromosomal Location
2p23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Fructose and mannose metabolism, Metabolic pathways
Field of Research
Fructose and mannose metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
32.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KHK
Species
Human
Protein ID
NP_000212
Overview
Recombinant protein of human ketohexokinase (fructokinase) (KHK), transcript variant a
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3795
Uniprot URL
https://www.uniprot.org/uniprot/P50053
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000221
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000212
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