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CTP synthase (CTPS1) (NM_001905) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate) . This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Overview

Recombinant protein of human CTP synthase (CTPS)

Synonyms

CTPS; GATD5; GATD5A; IMD24

Gene ID

1503

UniProt

P17812

Accession Number mRNA

NM_001905

Chromosomal Location

1p34.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Pyrimidine metabolism

Field of Research

Metabolic pathways, Pyrimidine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

66.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CTPS1

Species

Human

Protein ID

NP_001896

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1503

Uniprot URL

https://www.uniprot.org/uniprot/P17812

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001905

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001896

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