ADFP (PLIN2) (NM_001122) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
Synonyms
ADFP; ADRP
Gene ID
123
UniProt
Q99541, Q6FHZ7
Accession Number mRNA
NM_001122
Chromosomal Location
9p22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
47.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLIN2
Species
Human
Protein ID
NP_001113
Overview
Recombinant protein of human adipose differentiation-related protein (ADFP)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/123
Uniprot URL
https://www.uniprot.org/uniprot/Q99541
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001122
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001113
Curated Selection
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