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ADFP (PLIN2) (NM_001122) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Synonyms

ADFP; ADRP

Gene ID

123

UniProt

Q99541, Q6FHZ7

Accession Number mRNA

NM_001122

Chromosomal Location

9p22.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

47.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PLIN2

Species

Human

Protein ID

NP_001113

Overview

Recombinant protein of human adipose differentiation-related protein (ADFP)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/123

Uniprot URL

https://www.uniprot.org/uniprot/Q99541

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001122

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001113

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