CHST12 (NM_018641) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]
Synonyms
C4S-2; C4ST-2; C4ST2
Gene ID
55501
UniProt
Q9NRB3, A0A024R860
Accession Number mRNA
NM_018641
Chromosomal Location
7p22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chondroitin sulfate biosynthesis, Sulfur metabolism
Field of Research
Chondroitin sulfate biosynthesis, Sulfur metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
48.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHST12
Species
Human
Protein ID
NP_061111
Overview
Recombinant protein of human carbohydrate (chondroitin 4) sulfotransferase 12 (CHST12)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55501
Uniprot URL
https://www.uniprot.org/uniprot/Q9NRB3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018641
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_061111
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