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UBE2H (NM_003344) Human Recombinant Protein

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq, Feb 2011]

Overview

Recombinant protein of human ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) (UBE2H), transcript variant 1

Synonyms

E2-20K; GID3; UBC8; UBCH; UBCH2

Gene ID

7328

UniProt

P62256, A4D1L5

Accession Number mRNA

NM_003344

Chromosomal Location

7q32.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

20.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

UBE2H

Species

Human

Protein ID

NP_003335

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7328

Uniprot URL

https://www.uniprot.org/uniprot/P62256

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003344

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003335

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