RIP2 (RIPK2) (NM_003821) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human receptor-interacting serine-threonine kinase 2 (RIPK2)

Synonyms

CARD3; CARDIAK; CCK; GIG30; RICK; RIP2

Gene ID

8767

UniProt

O43353, A0A0S2Z4Z8

Accession Number mRNA

NM_003821

Chromosomal Location

8q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Neurotrophin signaling pathway, NOD-like receptor signaling pathway

Field of Research

Neurotrophin signaling pathway, NOD-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

61 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.