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Rab4 (RAB4A) (NM_004578) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

Overview

Recombinant protein of human RAB4A, member RAS oncogene family (RAB4A)

Synonyms

HRES-1; HRES-1/RAB4; HRES1; RAB4

Gene ID

5867

UniProt

P20338, A0A024R3U9

Accession Number mRNA

NM_004578

Chromosomal Location

1q42.13

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis

Field of Research

Endocytosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

24.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RAB4A

Species

Human

Protein ID

NP_004569

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5867

Uniprot URL

https://www.uniprot.org/uniprot/P20338

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004578

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004569

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