IGFBP2 (NM_000597) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II) . The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
Overview
Recombinant protein of human insulin-like growth factor binding protein 2, 36kDa (IGFBP2)
Synonyms
IBP2; IGF-BP53
Gene ID
3485
UniProt
P18065
Accession Number mRNA
NM_000597
Chromosomal Location
2q35
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein
Molecular Weight
35 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IGFBP2
Species
Human
Protein ID
NP_000588
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3485
Uniprot URL
https://www.uniprot.org/uniprot/P18065
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000597
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000588
Frequently Asked Questions
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