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FBXO27 (NM_178820) Human Recombinant Protein

Product Specifications

Background

Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM, Mar 2008]

Overview

Recombinant protein of human F-box protein 27 (FBXO27)

Synonyms

FBG5; Fbx27

Gene ID

126433

UniProt

Q8NI29, A0A384MR61

Accession Number mRNA

NM_178820

Chromosomal Location

19q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

31.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FBXO27

Species

Human

Protein ID

NP_849142

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/126433

Uniprot URL

https://www.uniprot.org/uniprot/Q8NI29

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_178820

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_849142

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