MAD2L1 binding protein (MAD2L1BP) (NM_014628) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1) . MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Synonyms
CMT2
Gene ID
9587
UniProt
Q15013
Accession Number mRNA
NM_014628
Chromosomal Location
6p21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
30.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MAD2L1BP
Species
Human
Protein ID
NP_055443
Overview
Recombinant protein of human MAD2L1 binding protein (MAD2L1BP), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9587
Uniprot URL
https://www.uniprot.org/uniprot/Q15013
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014628
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055443
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