GGPS1 (NM_004837) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]
Synonyms
GGPPS; GGPPS1
Gene ID
9453
UniProt
O95749
Accession Number mRNA
NM_004837
Chromosomal Location
1q42.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Terpenoid backbone biosynthesis
Field of Research
Metabolic pathways, Terpenoid backbone biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
34.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GGPS1
Species
Human
Protein ID
NP_004828
Overview
Recombinant protein of human geranylgeranyl diphosphate synthase 1 (GGPS1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9453
Uniprot URL
https://www.uniprot.org/uniprot/O95749
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004837
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004828
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