Carboxypeptidase A (CPA1) (NM_001868) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]
Overview
Recombinant protein of human carboxypeptidase A1 (pancreatic) (CPA1)
Synonyms
CPA
Gene ID
1357
UniProt
P15085
Accession Number mRNA
NM_001868
Chromosomal Location
7q32.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein
Molecular Weight
45.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CPA1
Species
Human
Protein ID
NP_001859
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1357
Uniprot URL
https://www.uniprot.org/uniprot/P15085
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001868
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001859
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