TNFAIP8 (NM_014350) Human Recombinant Protein
Product Specifications
Background
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.[UniProtKB/Swiss-Prot Function]
Synonyms
GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
Gene ID
25816
UniProt
O95379
Accession Number mRNA
NM_014350
Chromosomal Location
5q23.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
22.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TNFAIP8
Species
Human
Protein ID
NP_055165
Overview
Recombinant protein of human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25816
Uniprot URL
https://www.uniprot.org/uniprot/O95379
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014350
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055165
Curated Selection
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