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TXNL2 (GLRX3) (NM_006541) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Overview

Recombinant protein of human glutaredoxin 3 (GLRX3)

Synonyms

GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3

Gene ID

10539

UniProt

O76003, A0A140VJK1

Accession Number mRNA

NM_006541

Chromosomal Location

10q26.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

37.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GLRX3

Species

Human

Protein ID

NP_006532

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10539

Uniprot URL

https://www.uniprot.org/uniprot/O76003

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006541

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006532

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