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Lumican (LUM) (NM_002345) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human lumican (LUM)

Synonyms

LDC; SLRR2D

Gene ID

4060

UniProt

P51884, A0A384N669

Accession Number mRNA

NM_002345

Chromosomal Location

12q21.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

36.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LUM

Species

Human

Protein ID

NP_002336

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4060

Uniprot URL

https://www.uniprot.org/uniprot/P51884

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002345

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002336

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