Lumican (LUM) (NM_002345) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]
Synonyms
LDC; SLRR2D
Gene ID
4060
UniProt
P51884, A0A384N669
Accession Number mRNA
NM_002345
Chromosomal Location
12q21.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
36.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LUM
Species
Human
Protein ID
NP_002336
Overview
Recombinant protein of human lumican (LUM)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4060
Uniprot URL
https://www.uniprot.org/uniprot/P51884
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002345
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002336
Curated Selection
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