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HNRNPC (NM_001077442) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Synonyms

C1; C2; HNRNP; HNRPC; SNRPC

Gene ID

3183

UniProt

P07910

Accession Number mRNA

NM_001077442

Chromosomal Location

14q11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Spliceosome

Field of Research

Spliceosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

33.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HNRNPC

Species

Human

Protein ID

NP_001070910

Overview

Purified recombinant protein of Homo sapiens heterogeneous nuclear ribonucleoprotein C (C1/C2) (HNRNPC), transcript variant 3

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3183

Uniprot URL

https://www.uniprot.org/uniprot/P07910

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001077442

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001070910

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