HNRNPC (NM_001077442) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
C1; C2; HNRNP; HNRPC; SNRPC
Gene ID
3183
UniProt
P07910
Accession Number mRNA
NM_001077442
Chromosomal Location
14q11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Spliceosome
Field of Research
Spliceosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
33.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HNRNPC
Species
Human
Protein ID
NP_001070910
Overview
Purified recombinant protein of Homo sapiens heterogeneous nuclear ribonucleoprotein C (C1/C2) (HNRNPC), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3183
Uniprot URL
https://www.uniprot.org/uniprot/P07910
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001077442
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001070910
Curated Selection
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