GARS1 (NM_002047) Human Recombinant Protein
Product Specifications
Background
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Synonyms
CMT2D; DSMAV; GARS; GlyRS; HMN5; HMN5A; SMAD1; SMAJI
Gene ID
2617
UniProt
P41250, A0A090N8G0
Accession Number mRNA
NM_002047
Chromosomal Location
7p14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Aminoacyl-tRNA biosynthesis
Field of Research
Aminoacyl-tRNA biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
83 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GARS1
Species
Human
Protein ID
NP_002038
Overview
Recombinant protein of human glycyl-tRNA synthetase (GARS)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2617
Uniprot URL
https://www.uniprot.org/uniprot/P41250
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002047
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002038
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