ABI3 (NM_016428) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Overview
Recombinant protein of human ABI family, member 3 (ABI3), transcript variant 1
Synonyms
NESH; SSH3BP3
Gene ID
51225
UniProt
Q9P2A4
Accession Number mRNA
NM_016428
Chromosomal Location
17q21.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
38.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ABI3
Species
Human
Protein ID
NP_057512
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51225
Uniprot URL
https://www.uniprot.org/uniprot/Q9P2A4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016428
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057512
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