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ABI3 (NM_016428) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Overview

Recombinant protein of human ABI family, member 3 (ABI3), transcript variant 1

Synonyms

NESH; SSH3BP3

Gene ID

51225

UniProt

Q9P2A4

Accession Number mRNA

NM_016428

Chromosomal Location

17q21.32

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

38.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ABI3

Species

Human

Protein ID

NP_057512

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51225

Uniprot URL

https://www.uniprot.org/uniprot/Q9P2A4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016428

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057512

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