P60 CAF1 (CHAF1B) (NM_005441) Human Recombinant Protein
Product Specifications
Background
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
Synonyms
CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; MPHOSPH7; MPP7
Gene ID
8208
UniProt
Q13112
Accession Number mRNA
NM_005441
Chromosomal Location
21q22.12-q22.13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
61.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHAF1B
Species
Human
Protein ID
NP_005432
Overview
Recombinant protein of human chromatin assembly factor 1, subunit B (p60) (CHAF1B)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8208
Uniprot URL
https://www.uniprot.org/uniprot/Q13112
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005441
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005432
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