MCC (NM_002387) Human Recombinant Protein
Product Specifications
Background
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
MCC1
Gene ID
4163
UniProt
P23508
Accession Number mRNA
NM_002387
Chromosomal Location
5q22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
92.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MCC
Species
Human
Protein ID
NP_002378
Overview
Recombinant protein of human mutated in colorectal cancers (MCC), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4163
Uniprot URL
https://www.uniprot.org/uniprot/P23508
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002387
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002378
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