PEX14 (NM_004565) Human Recombinant Protein
Product Specifications
Background
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human peroxisomal biogenesis factor 14 (PEX14)
Synonyms
DJ734G22.2; NAPP2; PBD13A; Pex14p
Gene ID
5195
UniProt
O75381
Accession Number mRNA
NM_004565
Chromosomal Location
1p36.22
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
41.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PEX14
Species
Human
Protein ID
NP_004556
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5195
Uniprot URL
https://www.uniprot.org/uniprot/O75381
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004565
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004556
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