RTN4IP1 (NM_032730) Human Recombinant Protein
Product Specifications
Background
This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Synonyms
NIMP; OPA10
Gene ID
84816
UniProt
Q8WWV3
Accession Number mRNA
NM_032730
Chromosomal Location
6q21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
38.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RTN4IP1
Species
Human
Protein ID
NP_116119
Overview
Recombinant protein of human reticulon 4 interacting protein 1 (RTN4IP1), nuclear gene encoding mitochondrial protein
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84816
Uniprot URL
https://www.uniprot.org/uniprot/Q8WWV3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032730
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_116119
Curated Selection
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