PGAP4 (NM_032342) Human Recombinant Protein
Product Specifications
Background
Golgi-resident glycosylphosphatidylinositol (GPI) -N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins (PubMed:29374258) . Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2 (PubMed:29374258) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human chromosome 9 open reading frame 125 (C9orf125)
Synonyms
C9orf125; TMEM246
Gene ID
84302
UniProt
Q9BRR3, A0A024R188
Accession Number mRNA
NM_032342
Chromosomal Location
9q31.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
46.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PGAP4
Species
Human
Protein ID
NP_115718
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84302
Uniprot URL
https://www.uniprot.org/uniprot/Q9BRR3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032342
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_115718
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