PGAP4 (NM_032342) Human Recombinant Protein

Product Specifications

Background

Golgi-resident glycosylphosphatidylinositol (GPI) -N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins (PubMed:29374258) . Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2 (PubMed:29374258) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human chromosome 9 open reading frame 125 (C9orf125)

Synonyms

C9orf125; TMEM246

Gene ID

84302

UniProt

Q9BRR3, A0A024R188

Accession Number mRNA

NM_032342

Chromosomal Location

9q31.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

46.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.