DERL2 (NM_016041) Human Recombinant Protein
Product Specifications
Background
Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]) .[supplied by OMIM, Mar 2008]
Overview
Recombinant protein of human Der1-like domain family, member 2 (DERL2)
Synonyms
CGI-101; derlin-2; DERtrin-2; F-LAN-1; F-LANa; FLANa
Gene ID
51009
UniProt
Q9GZP9
Accession Number mRNA
NM_016041
Chromosomal Location
17p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
27.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DERL2
Species
Human
Protein ID
NP_057125
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51009
Uniprot URL
https://www.uniprot.org/uniprot/Q9GZP9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016041
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057125
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