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GST3 (GSTP1) (NM_000852) Human Recombinant Protein

Product Specifications

Background

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human glutathione S-transferase pi 1 (GSTP1)

Synonyms

DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI

Gene ID

2950

UniProt

P09211, V9HWE9

Accession Number mRNA

NM_000852

Chromosomal Location

11q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer

Field of Research

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

23.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GSTP1

Species

Human

Protein ID

NP_000843

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2950

Uniprot URL

https://www.uniprot.org/uniprot/P09211

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000852

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000843

Frequently Asked Questions

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