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Trfp (MED20) (NM_004275) Human Recombinant Protein

Product Specifications

Background

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]

Overview

Recombinant protein of human mediator complex subunit 20 (MED20)

Synonyms

PRO0213; SRB2; TRFP

Gene ID

9477

UniProt

Q9H944

Accession Number mRNA

NM_004275

Chromosomal Location

6p21.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

23 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MED20

Species

Human

Protein ID

NP_004266

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9477

Uniprot URL

https://www.uniprot.org/uniprot/Q9H944

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004275

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004266

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