Trfp (MED20) (NM_004275) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Synonyms
PRO0213; SRB2; TRFP
Gene ID
9477
UniProt
Q9H944
Accession Number mRNA
NM_004275
Chromosomal Location
6p21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
23 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MED20
Species
Human
Protein ID
NP_004266
Overview
Recombinant protein of human mediator complex subunit 20 (MED20)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9477
Uniprot URL
https://www.uniprot.org/uniprot/Q9H944
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004275
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004266
Curated Selection
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