ISG20 (NM_002201) Human Recombinant Protein
Product Specifications
Background
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human interferon stimulated exonuclease gene 20kDa (ISG20)
Synonyms
CD25; HEM45
Gene ID
3669
UniProt
Q96AZ6
Accession Number mRNA
NM_002201
Chromosomal Location
15q26.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
20.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ISG20
Species
Human
Protein ID
NP_002192
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3669
Uniprot URL
https://www.uniprot.org/uniprot/Q96AZ6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002201
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002192
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