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ISG20 (NM_002201) Human Recombinant Protein

Product Specifications

Background

Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human interferon stimulated exonuclease gene 20kDa (ISG20)

Synonyms

CD25; HEM45

Gene ID

3669

UniProt

Q96AZ6

Accession Number mRNA

NM_002201

Chromosomal Location

15q26.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

20.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ISG20

Species

Human

Protein ID

NP_002192

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3669

Uniprot URL

https://www.uniprot.org/uniprot/Q96AZ6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002201

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002192

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