NARS2 (NM_024678) Human Recombinant Protein

Product Specifications

Background

This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24) . [provided by RefSeq, Mar 2015]

Overview

Recombinant protein of human asparaginyl-tRNA synthetase 2, mitochondrial (putative) (NARS2), nuclear gene encoding mitochondrial protein

Synonyms

AsnRS; DFNB94; SLM5

Gene ID

79731

UniProt

Q96I59

Accession Number mRNA

NM_024678

Chromosomal Location

11q14.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Aminoacyl-tRNA biosynthesis

Field of Research

Aminoacyl-tRNA biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

53.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.