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HES6 (NM_018645) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Dec 2008]

Overview

Recombinant protein of human hairy and enhancer of split 6 (Drosophila) (HES6), transcript variant 1

Synonyms

BHLHb41; bHLHc23; C-HAIRY1; HES-6

Gene ID

55502

UniProt

Q96HZ4

Accession Number mRNA

NM_018645

Chromosomal Location

2q37.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

23.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HES6

Species

Human

Protein ID

NP_061115

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55502

Uniprot URL

https://www.uniprot.org/uniprot/Q96HZ4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018645

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_061115

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