STK25 (NM_006374) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Synonyms
SOK1; YSK1
Gene ID
10494
UniProt
O00506, A0A024R4B2
Accession Number mRNA
NM_006374
Chromosomal Location
2q37.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
47.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STK25
Species
Human
Protein ID
NP_006365
Overview
Purified recombinant protein of Homo sapiens serine/threonine kinase 25 (STE20 homolog, yeast) (STK25)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10494
Uniprot URL
https://www.uniprot.org/uniprot/O00506
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006374
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006365
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