FMO2 (NM_001460) Human Recombinant Protein
Product Specifications
Background
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Overview
Recombinant protein of human flavin containing monooxygenase 2 (non-functional) (FMO2)
Synonyms
FMO1B1
Gene ID
2327
UniProt
Q99518, Q5JPC7
Accession Number mRNA
NM_001460
Chromosomal Location
1q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Drug metabolism - cytochrome P450
Field of Research
Drug metabolism - cytochrome P450
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
53.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FMO2
Species
Human
Protein ID
NP_001451
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2327
Uniprot URL
https://www.uniprot.org/uniprot/Q99518
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001460
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001451
Frequently Asked Questions
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