HBA-T2 (HBB) (NM_000518) Human Recombinant Protein
Product Specifications
Background
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
Synonyms
Beta-globin; CD113t-C; ECYT6
Gene ID
3043
UniProt
P68871, D9YZU5
Accession Number mRNA
NM_000518
Chromosomal Location
11p15.4
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
15.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HBB
Species
Human
Protein ID
NP_000509
Overview
Recombinant protein of human hemoglobin, beta (HBB)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3043
Uniprot URL
https://www.uniprot.org/uniprot/P68871
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000518
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000509
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