MAD2 (MAD2L1) (NM_002358) Human Recombinant Protein
Product Specifications
Background
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human MAD2 mitotic arrest deficient-like 1 (yeast) (MAD2L1)
Synonyms
HSMAD2; MAD2
Gene ID
4085
UniProt
Q13257
Accession Number mRNA
NM_002358
Chromosomal Location
4q27
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation
Field of Research
Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
23.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MAD2L1
Species
Human
Protein ID
NP_002349
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4085
Uniprot URL
https://www.uniprot.org/uniprot/Q13257
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002358
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002349
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