Ferritin Light Chain (FTL) (NM_000146) Human Recombinant Protein
Product Specifications
Background
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
Synonyms
LFTD; NBIA3
Gene ID
2512
UniProt
P02792, A0A384MDR3
Accession Number mRNA
NM_000146
Chromosomal Location
19q13.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
19.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FTL
Species
Human
Protein ID
NP_000137
Overview
Recombinant protein of human ferritin, light polypeptide (FTL)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2512
Uniprot URL
https://www.uniprot.org/uniprot/P02792
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000146
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000137
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