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Cyclophilin E (PPIE) (NM_203457) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]

Overview

Purified recombinant protein of Homo sapiens peptidylprolyl isomerase E (cyclophilin E) (PPIE), transcript variant 3

Synonyms

CYP-33; CYP33

Gene ID

10450

UniProt

Q9UNP9

Accession Number mRNA

NM_203457

Chromosomal Location

1p34.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Spliceosome

Field of Research

Spliceosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

26 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPIE

Species

Human

Protein ID

NP_982282

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10450

Uniprot URL

https://www.uniprot.org/uniprot/Q9UNP9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_203457

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_982282

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