CIAO2A (NM_032231) Human Recombinant Protein
Product Specifications
Background
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004) . As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004) . May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227) .[UniProtKB/Swiss-Prot Function]
Synonyms
CIA2A; FAM96A
Gene ID
84191
UniProt
Q9H5X1
Accession Number mRNA
NM_032231
Chromosomal Location
15q22.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
18.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CIAO2A
Species
Human
Protein ID
NP_115607
Overview
Recombinant protein of human family with sequence similarity 96, member A (FAM96A), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84191
Uniprot URL
https://www.uniprot.org/uniprot/Q9H5X1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032231
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_115607
Curated Selection
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