TOE1 (NM_025077) Human Recombinant Protein
Product Specifications
Background
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing (PubMed:28092684) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human target of EGR1, member 1 (nuclear) (TOE1)
Synonyms
FLJ13949; hCaf1z; PCH7
Gene ID
114034
UniProt
Q96GM8
Accession Number mRNA
NM_025077
Chromosomal Location
1p34.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Stem cell - Pluripotency, Transcription Factors
Molecular Weight
56.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TOE1
Species
Human
Protein ID
NP_079353
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/114034
Uniprot URL
https://www.uniprot.org/uniprot/Q96GM8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025077
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079353
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