XLF (NHEJ1) (NM_024782) Human Recombinant Protein
Product Specifications
Background
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]
Synonyms
XLF
Gene ID
79840
UniProt
Q9H9Q4
Accession Number mRNA
NM_024782
Chromosomal Location
2q35
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Non-homologous end-joining
Field of Research
Non-homologous end-joining
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
33.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NHEJ1
Species
Human
Protein ID
NP_079058
Overview
Recombinant protein of human nonhomologous end-joining factor 1 (NHEJ1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79840
Uniprot URL
https://www.uniprot.org/uniprot/Q9H9Q4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024782
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079058
Curated Selection
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