XLF (NHEJ1) (NM_024782) Human Recombinant Protein

Product Specifications

Background

Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human nonhomologous end-joining factor 1 (NHEJ1)

Synonyms

XLF

Gene ID

79840

UniProt

Q9H9Q4

Accession Number mRNA

NM_024782

Chromosomal Location

2q35

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Non-homologous end-joining

Field of Research

Non-homologous end-joining

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

33.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.