DPP3 (NM_130443) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012]
Overview
Recombinant protein of human dipeptidyl-peptidase 3 (DPP3), transcript variant 2
Synonyms
DPPIII
Gene ID
10072
UniProt
Q9NY33, Q5JPB8
Accession Number mRNA
NM_130443
Chromosomal Location
11q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
82.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DPP3
Species
Human
Protein ID
NP_569710
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10072
Uniprot URL
https://www.uniprot.org/uniprot/Q9NY33
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_130443
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_569710
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