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COPE (NM_007263) Human Recombinant Protein

Product Specifications

Background

The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human coatomer protein complex, subunit epsilon (COPE), transcript variant 1

Synonyms

Epsilon-COP

Gene ID

11316

UniProt

O14579

Accession Number mRNA

NM_007263

Chromosomal Location

19p13.11

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

34.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

COPE

Species

Human

Protein ID

NP_009194

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11316

Uniprot URL

https://www.uniprot.org/uniprot/O14579

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007263

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_009194

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